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IL-11 Protein (AA 23-199)

IL11 Spezies: Maus Wirt: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Produktnummer ABIN2018055
  • Target Alle IL-11 (IL11) Proteine anzeigen
    IL-11 (IL11) (Interleukin 11 (IL11))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 23-199
    Spezies
    • 20
    • 9
    • 2
    • 2
    Maus
    Quelle
    • 13
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293T Cells
    Produktmerkmale
    ED50 < 3 ng/mL, measured in a cell proliferation assay using T11 cells.
    Reinheit
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant Murine Interleukin-11 (IL-11) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Murine Interleukin-11 (IL-11) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Andere Bezeichnung
    Interleukin-11(IL-11) (IL11 Produkte)
    Synonyme
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    Hintergrund
    Interleukin-11 (IL-11) is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1alpha-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 contains no cysteine residues or potential glycosylation sites. IL-11 has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell dependent development of specific immunoglobulin-secreting B cell.
    Synonyms: IL-11
    Molekulargewicht
    21 kDa, observed by reducing SDS-PAGE.
    UniProt
    P47873
    Pathways
    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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