IL-9 Protein (AA 19-144)

Produktnummer ABIN2018029

Dieses Recombinant IL-9-Protein wird in CHO Cells produziert.

Kurzübersicht für IL-9 Protein (AA 19-144) (ABIN2018029)

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: CHO Cells

Reinheit: > 95 % as analyzed by SDS-PAGE and HPLC.

Produktdetails

Proteineigenschaft: AA 19-144

Produktmerkmale: ED50 < 1 ng/mL, measured in a cell proliferation assay using MO7e cells, corresponding to a specific activity of > 1x10^6 units/mg.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant human Interlerkin 9 (IL-9) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-9 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Andere Bezeichnung: Interleukin 9 (IL-9)

Hintergrund: Interleukin 9, also known as IL9, is a cytokine (cell signalling molecule) belonging to the group of interleukins. The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Synonyms: p40 cytokine, T-cell growth factor p40

Molekulargewicht: 25-40 kDa, observed by non-reducing SDS-PAGE.

UniProt: P15248

Pathways: JAK-STAT Signalweg