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IL-5 Protein (AA 21-133)

IL5 Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Produktnummer ABIN2018026
  • Target Alle IL-5 (IL5) Proteine anzeigen
    IL-5 (IL5) (Interleukin 5 (IL5))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 21-133
    Spezies
    • 20
    • 15
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 27
    • 17
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    CHO Cells
    Produktmerkmale
    ED50 < 0.5 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 2x10^6 units/mg.
    Reinheit
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant Murine Interlerkin 5 (IL-5) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmIL-5 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    IL-5 (IL5) (Interleukin 5 (IL5))
    Andere Bezeichnung
    Interleukin 5 (IL-5) (IL5 Produkte)
    Synonyme
    EDF Protein, IL-5 Protein, TRF Protein, Il-5 Protein, IL5 Protein, interleukin 5 Protein, IL5 Protein, Il5 Protein
    Hintergrund
    Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Murine IL-5 is homodimeric protein with molecular weight ranging from 25 to 40 kDa due to glycosylation.
    Synonyms: EDF, BCDFII, TRF
    Molekulargewicht
    25-40 kDa, observed by non-reducing SDS-PAGE.
    UniProt
    P04401
    Pathways
    JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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