IGFBP2 Protein (AA 40-325) (His tag)

Produktnummer ABIN2017975

Produktdetails

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 40-325

Spezies: Human

Quelle: HEK-293T Cells

Aufreinigungstag / Konjugat: Dieses IGFBP2 Protein ist gelabelt mit His tag.

Produktmerkmale: ED50 < 2 μg/mL, measured in a bioassay using FDC-P1 cells in the presence of 15 ng/mL human IGF-II.
AA 40-325, expressed with C-terminal 6xHis.

Reinheit: > 95 % as analyzed by SDS-PAGE.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant human IGF-BP-2, Hisremains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human IGF-BP-2, His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Abstract: IGFBP2 Produkte

Hintergrund: IGF-BP-2,also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II, with a much higher binding affinity to IGF-II than IGF-I. IGF-BP-2 has been shown to inhibitand stimulate the growth promoting effects of IGFs, thus serving as a regulator for IGF distribution, function and activity.
Synonyms: Insulin-like growth factor-binding protein 2, IBP-2, BP-2

Molekulargewicht: 6-20 kDa, observed by reducing SDS-PAGE.

UniProt: P18065

Pathways: Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation