GM-CSF Protein (AA 18-144)
Kurzübersicht für GM-CSF Protein (AA 18-144) (ABIN2017901)
Target
Alle GM-CSF (CSF2) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 18-144
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Produktmerkmale
- ED50 < 5 pg/mL, measured in a cell proliferation assay using FDC-P1 cells, corresponding to a specific activity of > 2x10^8 units/mg.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Rat Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rrGM-CSF should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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Andere Bezeichnung
- Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
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Hintergrund
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Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. On mature hematopoietic, monocytes/macrophages and eosinophils.
Synonyms: Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha -
Molekulargewicht
- 16-26 kDa, observed by non-reducing SDS-PAGE.
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UniProt
- P48750
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Pathways
- JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin
Target
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