FABP Heart Protein

Produktnummer ABIN1880369

Dieses Recombinant FABP Heart-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für FABP Heart Protein (ABIN1880369)

Target: FABP Heart

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % by SDS-PAGE

Produktdetails

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 20 mM Tris-HCL, 140 mM NaCl, 2 mM EDTA (pH 8.0)

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Antigendetails

Target: FABP Heart

Hintergrund: Heart-type fatty acid binding protein (hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene. It is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. H-FABP is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of the pain. It is also the biomarker for heart injury. In addition to its diagnostic potential, H-FABP also has prognostic value. Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or Mi at one year.

Molekulargewicht: 15 kDa