FABP Heart (Active) Protein

Produktnummer ABIN1880337

Dieses Native FABP Heart-Protein wird in Human exprimiert.

Kurzübersicht für FABP Heart (Active) Protein (ABIN1880337)

Target: FABP Heart

Protein-Typ: Native

Biologische Aktivität: Active

Spezies: Human

Quelle: Human

Applikation: Chemiluminescence Immunoassay (CLIA), ELISA, Immunohistochemistry (IHC), Radioimmunoassay (RIA), Western Blotting (WB)

Produktdetails

Aufreinigung: Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM PBS( pH 7.4).

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Shipat 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: FABP Heart

Hintergrund:

Synonyms: Fattyacid-binding protein 3, FABP3, Heart-type fatty acid-binding protein, H-FABP, Mammary-derived growth inhibitor, MDGI, Muscle fatty acid-binding protein, M-FABP, FABP11

Description: Purified human FABP3 protein.

Background: Heart-type fatty acid binding protein (hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene. It is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. H-FABP is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of the pain. It is also the biomarker for heart injury. In addition to its diagnostic potential, H-FABP also has prognostic value. Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or Mi at one year.