C-Peptide Protein

Produktnummer ABIN1880359

Recombinant C-Peptide-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für C-Peptide Protein (ABIN1880359)

Target: C-Peptide

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % by HPLC & SDS-PAGE

Produktdetails

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10mM PBS (pH 7.5)

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Antigendetails

Target: C-Peptide

Hintergrund: Connecting peptide, or C-peptide, is a short 31-amino-acid protein that connects insulin's A-chain to its B-chain in the proinsulin molecule. C-peptide has been shown to bind to the surface of a number of cell types such as neuronal, endothelial, fibroblast and renal tubular, at nanomolar concentrations to a receptor that is likely G-protein-coupled. It has been found to exert beneficial effects in many tissues affected by diabetic microvascular complications, including the kidneys. C-peptide at physiological concentrations effectively reduces diabetes-induced glomerular hyperfiltration via constriction of the afferent arteriole, dilation of the efferent arteriole, and inhibition of tubular reabsorption in experimental models of type 1 diabetes.