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NEDD8 Protein (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8) (AA 1-76) (His tag,SUMO Tag)

NEDD8 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1692401
$88.00
Zzgl. Versandkosten $45.00
Lieferung in 4 Werktagen
  • Target Alle NEDD8 Proteine anzeigen
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-76
    Spezies
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 3
    • 3
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses NEDD8 Protein ist gelabelt mit His tag,SUMO Tag.
    Verwendungszweck
    Recombinant Human NEDD8 (N-6His, SUMO tag)
    Sequenz
    MGHHHHHHGS LQDSEVNQEA KPEVKPEVKP ETHINLKVSD GSSEIFFKIK KTTPLRRLME AFAKRQGKEM DSLRFLYDGI RIQADQAPED LDMEDNDIIE AHREQIGGML IKVKTLTGKE IEIDIEPTDK VERIKERVEE KEGIPPQQQR LIYSGKQMND EKTAADYKIL GGSVLHLVLA LRGG
    Produktmerkmale
    Recombinant Human Neural precursor cell expressed developmentally down-regulated protein 8/NEDD8 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Gly76) of Human NEDD8 fused with a 6His tag at the N-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,5 % Trehalose, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    5 months
  • Target
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Andere Bezeichnung
    NEDD8 (NEDD8 Produkte)
    Synonyme
    NEDD-8, Rub1, CG10679, Dmel\\CG10679, NEDD8, dNEDD8, nedd8, ubiquitin, si:zc14a17.5, GB17785, DDBDRAFT_0218116, DDBDRAFT_0238041, DDB_0218116, DDB_0238041, nedd8.S, neural precursor cell expressed, developmentally down-regulated 8, neural precursor cell expressed, developmentally down-regulated gene 8, CG10679 gene product from transcript CG10679-RB, Nedd8, ubiquitin-like protein Nedd8, neural precursor cell expressed, developmentally down-regulated 8 L homeolog, NEDD8, Nedd8, nedd8, nedd8.L
    Sub Type
    Fusionprotein
    Hintergrund
    Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation. NEDD8 modification has therefore been implicated in cell cycle progression and cytoskeletal regulation.
    Alternative Names: Neural precursor cell expressed developmentally down-regulated protein 8, NEDD8, Neddylin, Ubiquitin-like protein Nedd8,
    Molekulargewicht
    20.9 kDa
    UniProt
    Q15843
    Pathways
    Ubiquitin Proteasome Pathway
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