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CTH Protein (AA 1-405)

Dieses Recombinant CTH-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN1692129

Kurzübersicht für CTH Protein (AA 1-405) (ABIN1692129)

Target

Alle CTH Proteine anzeigen
CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Protein-Typ

Recombinant

Spezies

  • 8
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 5
  • 4
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Proteineigenschaft

    AA 1-405

    Verwendungszweck

    Recombinant Human Cystathionine γ-Lyase/CTH

    Sequenz

    GHMQEKDASS QGFLPHFQHF ATQAIHVGQD PEQWTSRAVV PPISLSTTFK QGAPGQHSGF EYSRSGNPTR NCLEKAVAAL DGAKYCLAFA SGLAATVTIT HLLKAGDQII CMDDVYGGTN RYFRQVASEF GLKISFVDCS KIKLLEAAIT PETKLVWIET PTNPTQKVID IEGCAHIVHK HGDIILVVDN TFMSPYFQRP LALGADISMY SATKYMNGHS DVVMGLVSVN CESLHNRLRF LQNSLGAVPS PIDCYLCNRG LKTLHVRMEK HFKNGMAVAQ FLESNPWVEK VIYPGLPSHP QHELVKRQCT GCTGMVTFYI KGTLQHAEIF LKNLKLFTLA ESLGGFESLA ELPAIMTHAS VLKNDRDVLG ISDTLIRLSV GLEDEEDLLE DLDQALKAAH PPSGSHS

    Produktmerkmale

    Recombinant Human Cystathionine γ-Lyase/CTH

    Sterilität

    0.2 μm filtered

    Endotoxin-Niveau

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Rekonstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,20 % Glycerol, pH 7.4.

    Handhabung

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

    Andere Bezeichnung

    Cystathionine gamma-Lyase/CTH

    Hintergrund

    Recombinant Human Cystathionine γ-Lyase/CTH is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser405) of Human CTH.
    Cystathionine γ-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.

    Molekulargewicht

    44.7kDa

    UniProt

    P32929

    Pathways

    ER-Nucleus Signaling, Warburg Effekt
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