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TNFRSF12A Protein (Tumor Necrosis Factor Receptor Superfamily, Member 12A) (AA 1-79) (Fc Tag)

TNFRSF12A Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1691586
$313.50
Zzgl. Versandkosten $45.00
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  • Target Alle TNFRSF12A Proteine anzeigen
    TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-79
    Spezies
    • 12
    • 3
    Human
    Quelle
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses TNFRSF12A Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human TWEAK Receptor/TWEAK R/TNFRSF12A (C-Fc)
    Sequenz
    EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWVDDIEGRM DEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK
    Produktmerkmale
    Recombinant Human Tweak-Receptor/FN14 is produced by our mammalian expression system. The target protein is expressed with sequence (Met1-Trp79) of Human TNFRSF12A fused with a FC tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    5 months
  • Target
    TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
    Andere Bezeichnung
    TNFRSF12A (TNFRSF12A Produkte)
    Synonyme
    CD266, FN14, TWEAKR, AI255180, C87282, Fn14, HPIP, TWEAK-R, TweakR, TNF receptor superfamily member 12A, tumor necrosis factor receptor superfamily, member 12a, TNFRSF12A, Tnfrsf12a
    Sub Type
    Fusionprotein
    Hintergrund
    Tumor necrosis factor receptor superfamily member 12A(TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor. TNFRSF12A is a single-pass type I membrane protein, including a 27 aa signal peptide, a 53 aa extracellular domain, a 21 aa transmembrane domain and a 28 aa cytoplasmic domain. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A can be induced by FGF1 and phorbol ester. TNFRSF12A binds to TWEAK/TNFSF12A to initiate a signal transduction cascade, causing different cellular responses such as cell death, cell proliferation, and angiogenesis.
    Alternative Names: TNFRSF12A,Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor.
    Molekulargewicht
    35.6 kDa
    UniProt
    Q9NP84
    Pathways
    Apoptose, Regulation of Cell Size
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