Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HSPD1 Protein (partial)

HSPD1 Spezies: Bakterien Wirt: Escherichia coli (E. coli) Recombinant >90% WB, SDS, ELISA, Func
Produktnummer ABIN1686691
  • Target Alle HSPD1 Proteine anzeigen
    HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    partial
    Spezies
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Bakterien
    Quelle
    • 16
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    Western Blotting (WB), SDS-PAGE (SDS), ELISA, Functional Studies (Func)
    Sequenz
    EDPYEKIGAE LVKEVAKKTD DVAGDGTTTA TVLAQALVRE GLRNVAAGAN PLGLKRGIEK AVEKVTETLL KGAKEVETKE QIAATAAISA GDQSIGDLIA EAMDKVGNEG VITVEESNTF GLQLELTEGM RFDKGYISGY FVTDPERQEA VLEDPYILLV SSKVSTVKDL LPLXXXXXXX GKPLLIIAED VEGEALSTLV
    Spezifität
    ~65 kDa
    Aufreinigung
    Multi-Step Purified
    Reinheit
    >90%
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    This product has been certified >90% pure using SDS-PAGE analysis.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    Lot specific
    Buffer
    10 mM Tris pH 8, 105 mM NaCl, 5 mM EDTA
    Lagerung
    -20 °C
  • Sun, Shen, Liu, Tan, Tian, Luo, Lai, Dai, Guo: "Heat shock protein 65 promotes atherosclerosis through impairing the properties of high density lipoprotein." in: Atherosclerosis, Vol. 237, Issue 2, pp. 853-61, (2014) (PubMed).

    Adamus, Bonnah, Brown, David: "Detection of autoantibodies against heat shock proteins and collapsin response mediator proteins in autoimmune retinopathy." in: BMC ophthalmology, Vol. 13, pp. 48, (2013) (PubMed).

  • Target
    HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
    Abstract
    HSPD1 Produkte
    Synonyme
    CPN60 Protein, GROEL Protein, HLD4 Protein, HSP-60 Protein, HSP60 Protein, HSP65 Protein, HuCHA60 Protein, SPG13 Protein, chaperonin Protein, cpn60 Protein, groel Protein, hld4 Protein, hsp60 Protein, hsp65 Protein, spg13 Protein, 60kDa Protein, Hsp60 Protein, 12 Protein, BP5 Protein, CG12101 Protein, Cpn60 Protein, Dmel\\CG12101 Protein, Dmhsp60 Protein, G62 Protein, HSP60A Protein, Hsp60A Protein, IEF16 Protein, Mmp-P1 Protein, SSP 7506 Protein, d-hsp60 Protein, hsp60A Protein, l(1)10Ac Protein, l(1)BP5 Protein, l(1)G8 Protein, l(1)HM21 Protein, l(1)L12 Protein, l(1)dp025 Protein, cb863 Protein, fa04a05 Protein, fb22d10 Protein, fi27b05 Protein, id:ibd2197 Protein, sb:cb144 Protein, wu:fa04a05 Protein, wu:fb22d10 Protein, wu:fi04a12 Protein, wu:fi27b05 Protein, MIF4 Protein, MNA2 Protein, mopA Protein, groL Protein, crpA Protein, Hspd1-30p Protein, heat shock protein family D (Hsp60) member 1 Protein, heat shock protein family D (Hsp60) member 1 S homeolog Protein, 60 kDa heat shock protein, mitochondrial Protein, heat shock protein 1 (chaperonin) Protein, Heat shock protein 60A Protein, heat shock 60 protein 1 Protein, chaperone ATPase HSP60 Protein, molecular chaperone GroEL Protein, thermosome subunit Protein, chaperonin GroEL Protein, mitochondrial chaperonin Protein, heat shock protein family D member 1 Protein, HSPD1 Protein, hspd1.S Protein, hspd1 Protein, LOC100414401 Protein, Hspd1 Protein, Hsp60A Protein, HSP60 Protein, groEL Protein, MMP_RS07785 Protein, groEl Protein, LOC100136430 Protein
    Hintergrund
    HSP65 isolated from Mycobacterium bovis BCG, is a member of the HSP60 family of heat shock proteins (2, 3). HSP60s are mitochondrial chaperonins that are typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. HSP60s are a ubiquitous class of HSPs that specifically promote the folding and assembly of cellular polypeptides in an ATP-dependent manner (1). Specifically, sequence comparison of HSP65 from different mycobacterium strains showed that the protein sequence of M. bovis BCG is identical to that of M. tuberculosis, and very similar to that of M. leprae, the pathogens that cause tuberculosis and tuberculoid leprosy, respectively (2,4). Mycobacterium bovis BCG HSP65 was identified as the immunodominant antigen during mycobacterial diseases and vaccination. It is also believed to be the antigen that induces autoimmune disease, such as adjuvant arthritis in rats (5, 6).
    Molekulargewicht
    approx. 65 kDa
    UniProt
    Q1EHB9
    Pathways
    Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Sie sind hier:
Kundenservice