CD161 Protein (His tag)

Produktnummer ABIN1098668

Produktdetails

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CD161 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Killer cell lectin-like receptor subfamily B member 1, p35-2, STX4A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Andere Bezeichnung: KLRB1 (KLRB1 Produkte)

Synonyme: NKR-P1 Protein, KLRB1 Protein, 4930431A04Rik Protein, Gm4696 Protein, Klrb1g Protein, Klrb6 Protein, Ly-55 Protein, Ly55 Protein, NKR-P1G Protein, Nkrp-1e Protein, Nkrp1g Protein, CD161 Protein, CLEC5B Protein, NKR Protein, NKR-P1A Protein, NKRP1A Protein, hNKR-P1A Protein, Klrb1d Protein, Klrb1f Protein, Nkr-p1e Protein, killer cell lectin like receptor B1 Protein, killer cell lectin-like receptor subfamily B member 1 Protein, killer cell lectin-like receptor subfamily B, member 1 Protein, KLRB1 Protein, Klrb1 Protein

Hintergrund: Killer cell lectin-like receptor subfamily B member 1, also known as KLRB1, plays an inhibitory role on natural killer (NK) cells cytotoxicity. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. Recombinant human KLRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 21.0 kDa (183aa)

NCBI Accession: NP_002249