CXCL14 Protein (AA 35-111)
Kurzübersicht für CXCL14 Protein (AA 35-111) (ABIN1096464)
Target
Alle CXCL14 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 35-111
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Verwendungszweck
- Recombinant Human C-X-C Motif Chemokine 14/CXCL14
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Sequenz
- SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE
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Produktmerkmale
- Recombinant Human C-X-C Motif Chemokine 14 is produced by our E.coli expression system and the target gene encoding Ser35-Glu111 is expressed.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Kommentare
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Biological activity: ED50 is 1.0-10.0 ng/ml as determined by the ability of Recombinant CXCL14 to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Lyophilized from a 0.2 um filtered solution of 20 mM Tris-HCl, 1M NaCl, pH 8.5.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Haltbarkeit
- 3 weeks
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- CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))
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Andere Bezeichnung
- cxcl14
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Hintergrund
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Alternative Names: C-X-C Motif Chemokine 14, Chemokine BRAKm MIP-2G, Small-Inducible Cytokine B14, CXCL14, MIP2G, NJAC, SCYB14Human Chemokine (C-X-C Motif) Ligand 14 (CXCL14) is constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemoattractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 amino acid residues.
Alternative Names: C-X-C Motif Chemokine 14, Chemokine BRAKm MIP-2G, Small-Inducible Cytokine B14, CXCL14, MIP2G, NJAC, SCYB14 -
Molekulargewicht
- 9.4 kDa
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UniProt
- O95715
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Pathways
- Autophagie
Target
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