CNTF Protein (AA 2-200)

Produktnummer ABIN1096416

Dieses Recombinant CNTF-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für CNTF Protein (AA 2-200) (ABIN1096416)

Target: CNTF (Ciliary Neurotrophic Factor (CNTF))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 2-200

Verwendungszweck: Recombinant Human Ciliary Neurotrophic Factor/CNTF

Sequenz: AFTEHSPLTP HRRDLCSRSI WLARKIRSDL TALTESYVKH QGLNKNINLD SADGMPVAST DQWSELTEAE RLQENLQAYR TFHVLLARLL EDQQVHFTPT EGDFHQAIHT LLLQVAAFAY QIEELMILLE YKIPRNEADG MPINVGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRFISS HQTGIPARGS HYIANNKKM

Produktmerkmale: Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 um filtered solution of 20 mM TrisHCl, 100 mM Nacl,ph8.0.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 weeks

Antigendetails

Target: CNTF (Ciliary Neurotrophic Factor (CNTF))

Andere Bezeichnung: cntf

Hintergrund: Alternative Names: Ciliary Neurotrophic Factor, CNTFCiliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
Alternative Names: Ciliary Neurotrophic Factor, CNTF

Molekulargewicht: 22.93 kDa

UniProt: P26441

Pathways: JAK-STAT Signalweg