ATG3 Protein (AA 1-314)

Produktnummer ABIN1096065

Dieses Recombinant ATG3-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für ATG3 Protein (AA 1-314) (ABIN1096065)

Target: ATG3 (ATG3 Autophagy Related 3 (ATG3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 1-314

Verwendungszweck: Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3

Sequenz: GSMQNVINTV KGKALEVAEY LTPVLKESKF KETGVITPEE FVAAGDHLVH HCPTWQWATG EELKVKAYLP TGKQFLVTKN VPCYKRCKQM EYSDELEAII EEDDGDGGWV DTYHNTGITG ITEAVKEITL ENKDNIRLQD CSALCEEEED EDEGEAADME EYEESGLLET DEATLDTRKI VEACKAKTDA GGEDAILQTR TYDLYITYDK YYQTPRLWLF GYDEQRQPLT VEHMYEDISQ DHVKKTVTIE NHPHLPPPPM CSVHPCRHAE VMKKIIETVA EGGGELGVHM YLLIFLKFVQ AVIPTIEYDY TRHFTM

Produktmerkmale: Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3 is produced by our E.coli expression system and the target gene encoding Met1-Met314 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 um filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10 % Glycerol, pH 8.0.

Handhabung: minimize freeze-thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: ATG3 (ATG3 Autophagy Related 3 (ATG3))

Andere Bezeichnung: Ubiquitin-Like-Conjugating Enzyme ATG3/ATG3

Hintergrund: Alternative Names: Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, APG3-like, hApg3, Protein PC3-96, ATG3, APG3, APG3LRecombinant Human Ubiquitin-Like-Conjugating Enzyme ATG3/ATG3 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-His287) of Human ATG3 fused with a 6His tag at the C-terminus.
Ubiquitin-Like-Conjugating Enzyme ATG3 (ATG3) is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. ATG3 as a E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. As an autocatalytic E2-like enzyme, ATG3 also can catalyzes the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

Molekulargewicht: 36 kDa

UniProt: Q9NT62

Pathways: Autophagie