RPA3 Protein (AA 1-119, partial) (His tag)

Produktnummer ABIN1047599

Dieses Recombinant RPA3-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für RPA3 Protein (AA 1-119, partial) (His tag) (ABIN1047599)

Target: RPA3 (Replication Protein A3, 14kDa (RPA3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS), ELISA

Reinheit: 95 %

Produktdetails

Proteineigenschaft: AA 1-119, partial

Aufreinigungstag / Konjugat: Dieses RPA3 Protein ist gelabelt mit His tag.

Sequenz: MVDMMDLPRS RINAGMLAQF IDKPVCFVGR LEKIHPTGKM FILSDGEGKN GTIELMEPLD EEISGIVEVV GRVTAKATIL CTSYVQFKED SHPFDLGLYN EAVKIIHDFP QFYPLGIVQ

Spezifität: N-terminal 6xHis-tagged

Produktmerkmale: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref.7 Ref.9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. Ref.7 Ref.9

Anwendungsinformationen

Kommentare:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized or Liquid

Buffer: Liquid protein in buffer: 10 mM Tris-HCl, 1 mM EDTA, pH 8.0,50% glycerol

Lagerung: -20 °C

Antigendetails

Target: RPA3 (Replication Protein A3, 14kDa (RPA3))

Andere Bezeichnung: Replication protein A 14 kDa subunit

Hintergrund: Synonyms: Replication factor A protein 3

Molekulargewicht: 17.4 kD

UniProt: P35244

Pathways: Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA