PPT1 Produkte
(Palmitoyl-Protein Thioesterase 1 (PPT1))
Kategorien
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008].
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Ausgewählte PPT1 Kategorien
PPT1 Antikörper
High quality antibodies with extensive validation data.
PPT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PPT1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PPT1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (3)
- (5)
Kat. Nr.
ABIN1944801
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IHC (p)
Validierungen
- (7)
Kat. Nr.
ABIN1490802
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p), FACS
Validierungen
- (3)
Kat. Nr.
ABIN4913200
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PPT1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951472
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1146898
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1146899
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PPT1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316094
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7491183
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7578963
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PPT1 Produkten
: "Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses." in: Orphanet journal of rare diseases, Vol. 13, Issue 1, pp. 54, (2019) (PubMed).: "Reversible Cysteine Acylation Regulates the Activity of Human Palmitoyl-Protein Thioesterase 1 (PPT1)." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146466, (2016) (PubMed).
: "Quantitative analysis of PPT1 interactome in human neuroblastoma cells." in: Data in brief, Vol. 4, pp. 207-16, (2015) (PubMed).
: "The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting." in: Molecular and cellular biology, Vol. 32, Issue 10, pp. 1855-66, (2012) (PubMed).
: "The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37957-64, (2003) (PubMed).
: "The neuronal ceroid lipofuscinoses: mutations in different proteins result in similar disease." in: Neuromolecular medicine, Vol. 1, Issue 2, pp. 111-24, (2002) (PubMed).
: "Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2)." in: Current molecular medicine, Vol. 2, Issue 5, pp. 423-37, (2002) (PubMed).
: "Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 9, pp. 4316-9, (1996) (PubMed).
: "cDNA and genomic cloning of human palmitoyl-protein thioesterase (PPT), the enzyme defective in infantile neuronal ceroid lipofuscinosis." in: Genomics, Vol. 34, Issue 3, pp. 317-22, (1996) (PubMed).
: "Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis." in: Nature, Vol. 376, Issue 6541, pp. 584-7, (1995) (PubMed).
Synonyme und alternative Namen zu PPT1
palmitoyl-protein thioesterase 1 (PPT1), palmitoyl-protein thioesterase 1 (MGYG_00692), palmitoyl-protein thioesterase 1 (Ppt1), Palmitoyl-protein thioesterase 1 (ppt-1), palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) (ppt1), palmitoyl-protein thioesterase 1 L homeolog (ppt1.L), 9530043G02Rik, AA960502, C77813, CLN1, D4Ertd184e, INCL, PPT, Ppt, PPT-1, ppt1, wu:fj17f04, zgc:63969Bezeichner auf Proteinebene für PPT1
- ceroid-palmitoyl-palmitoyl-protein thioesterase 1
- palmitoyl-protein hydrolase 1
- palmitoyl-protein thioesterase 1
- PPT-1
- palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
- palmitoyl protein thioesterase
- Palmitoyl-protein hydrolase 1
- palmitoyl-protein thioesterase 1 L homeolog
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