PKC gamma Produkte
(Protein Kinase C, gamma (PRKCG))
Kategorien
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008].
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Ausgewählte PKC gamma Kategorien
PKC gamma Antikörper
High quality antibodies with extensive validation data.
PKC gamma ELISA Kits
Reliable ELISA kits for a wide range of species.
PKC gamma Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PKC gamma Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (2)
Kat. Nr.
ABIN703285
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN391009
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN562388
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene PKC gamma ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962223
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969722
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958929
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PKC gamma Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7563505
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7554315
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5509105
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PKC gamma Produkten
: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." in: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).: "Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKC? Activity and Regulates Purkinje Cell Dendritic Growth." in: Molecular neurobiology, (2015) (PubMed).
: "Extracts from Salvia-Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity." in: Journal of translational medicine, Vol. 12, pp. 236, (2015) (PubMed).
: "Increased protein kinase C gamma activity induces Purkinje cell pathology in a mouse model of spinocerebellar ataxia 14." in: Neurobiology of disease, Vol. 70, pp. 1-11, (2014) (PubMed).
: "Protein kinase C gamma mutations in spinocerebellar ataxia 14 increase kinase activity and alter membrane targeting." in: Brain : a journal of neurology, Vol. 128, Issue Pt 2, pp. 436-42, (2005) (PubMed).
: "Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 2254-61, (2004) (PubMed).
: "A Ras activation pathway dependent on Syk phosphorylation of protein kinase C." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 16, pp. 9470-5, (2003) (PubMed).
: "Spinocerebellar ataxia type 14 caused by a mutation in protein kinase C gamma." in: Archives of neurology, Vol. 60, Issue 12, pp. 1749-51, (2003) (PubMed).
: "Identification of a novel SCA14 mutation in a Dutch autosomal dominant cerebellar ataxia family." in: Neurology, Vol. 61, Issue 12, pp. 1760-5, (2003) (PubMed).
: "Protein kinase C gamma (PKC gamma): function of neuron specific isotype." in: Journal of biochemistry, Vol. 132, Issue 5, pp. 683-7, (2002) (PubMed).
Synonyme und alternative Namen zu PKC gamma
protein kinase C gamma (PRKCG), protein kinase C, gamma (Prkcg), protein kinase C gamma type (LOC484316), protein kinase C gamma (Prkcg), PKC, PKC-gamma, PKCC, Pkcc, PKCG, PKCgamma, PKCI, Prkc, Prkcc, PRKCG, RATPKCI, SCA14Bezeichner auf Proteinebene für PKC gamma
- protein kinase C, gamma
- protein kinase C gamma type-like
- protein kinase C gamma type
- PKC-gamma
- protein kinase C type I (gamma type)
- PKC-delta
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