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anti-F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) Antikörper

Bezeichnung:: anti-F-Box and Leucine-Rich Repeat Protein 3 Antikörper (FBXL3)

Auf www.antikoerper-online.de finden Sie aktuell 77 F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen F-Box and Leucine-Rich Repeat Protein 3 Kits (15) und F-Box and Leucine-Rich Repeat Protein 3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 102 F-Box and Leucine-Rich Repeat Protein 3 Produkte verfügbar.

Synonyme:: AU041772, AW212966, F7A7.240, F7A7_240, FBK, FBL3, Fbl3a, FBXL3, Fbxl3a, im:7153024, Ovtm, Play68, zgc:103721

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	FBXL3	26224	Q9UKT7
	FBXL3	50789	Q8C4V4
	FBXL3	306129
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Verknüpfte Pathways mit anti-F-Box and Leucine-Rich Repeat Protein 3 Antikörper

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Weitere Produktkategorien zu F-Box and Leucine-Rich Repeat Protein 3 Antikörper

Am meisten referenzierte anti-F-Box and Leucine-Rich Repeat Protein 3 Antikörper

Human Polyclonal FBXL3 Primary Antibody für ELISA, WB - ABIN251670 : Korge, Grudziecki, Kramer: Highly Efficient Genome Editing via CRISPR/Cas9 to Create Clock Gene Knockout Cells. in Journal of biological rhythms 2015 (PubMed)
Show all 2 Pubmed References
Dog (Canine) Polyclonal FBXL3 Primary Antibody für ELISA, WB - ABIN547745 : Albig, Neil, Schiemann: Fibulins 3 and 5 antagonize tumor angiogenesis in vivo. in Cancer research 2006 (PubMed)

Weitere Antikörper gegen F-Box and Leucine-Rich Repeat Protein 3 Interaktionspartner

Human F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) Interaktionspartner

FBXL3 was regulated by miR-4735-3p and suppressed cell proliferation and invasion in non-small cell lung cancer.
data indicate an oncogenic role of miR-181d in CRC by promoting glycolysis, and miR-181d/CRY2/FBXL3/c-myc feedback loop might be a therapeutic target for patients with CRC.
These results demonstrate that CRY2 stability controlled by FBXL3 plays a key role in the regulation of human sleep wake behavior.
CRY2 and FBXL3 cooperatively degrade c-MYC preventing the development of cancer.
Data show that CRISPR/Cas9 genome editing generated F-box and leucine-rich repeat protein 3 (Fbxl3) knockout in circadian clock model U2OS cells.
Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex.
Mutation in the Fbxl3 protein reveals distinct roles for CRY1 and CRY2 in the circadian molecular clockwork.
crystal structures of mammalian CRY2 in its apo, FAD-bound and FBXL3-SKP1-complexed forms
study demonstrates that the SCF(Fbxl3)ubiquitin ligase controls the oscillations of the circadian clock by mediating the degradation of Cry1 and Cry2 proteins

Mouse (Murine) F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) Interaktionspartner

CRY2 and FBXL3 cooperatively degrade c-MYC preventing the development of cancer.
Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex.
By analyzing the Fbxl3 and Cryptochrome 1 double-mutant mice, we found that FBXL3 also regulates the amplitudes of E-box-driven gene expression.
crystal structures of mammalian CRY2 in its apo, FAD-bound and FBXL3-SKP1-complexed forms
FBXL21 plays a dual role: protecting CRY 1/2 proteins (CRY) from FBXL3 degradation in the nucleus and promoting CRY degradation within the cytoplasm.
results are consistent with previous studies of mutants with extended circadian periods and suggest that disruption of FBXL3 is associated with mania-like behaviours in both mice and humans
In Ovtm mice, expression of the PERIOD proteins is reduced; however, the CRY proteins are unchanged; the loss of FBXL3 function leads to a stabilization of the CRY proteins, which leads to a global transcriptional repression of the Per and Cry genes.
study demonstrates that the SCF(Fbxl3)ubiquitin ligase controls the oscillations of the circadian clock by mediating the degradation of Cry1 and Cry2 proteins
studies reveal a central role for Fbxl3 in mammalian circadian timekeeping

F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.

Alternative names and synonyms associated with F-Box and Leucine-Rich Repeat Protein 3 (FBXL3)

F-box and leucine rich repeat protein 3 (FBXL3) Antikörper
F-box and leucine-rich repeat protein 3 (Fbxl3) Antikörper
F-box and leucine-rich repeat protein 3 L homeolog (fbxl3.L) Antikörper
F-box and leucine-rich repeat protein 3 (fbxl3) Antikörper
F-box and leucine rich repeat protein 3 (fbxl3) Antikörper
RNI-like superfamily protein (AT5G01720) Antikörper
F-box and leucine rich repeat protein 3 (Fbxl3) Antikörper
F-box and leucine-rich repeat protein 3a (fbxl3a) Antikörper

AU041772 Antikörper
AW212966 Antikörper
F7A7.240 Antikörper
F7A7_240 Antikörper
FBK Antikörper
FBL3 Antikörper
Fbl3a Antikörper
FBXL3 Antikörper
Fbxl3a Antikörper
im:7153024 Antikörper
Ovtm Antikörper
Play68 Antikörper
zgc:103721 Antikörper

Bezeichner auf Proteinebene für FBXL3

F-box and leucine-rich repeat protein 3A , F-box protein Fbl3a , F-box/LRR-repeat protein 3 , F-box/LRR-repeat protein 3A , F-box and leucine-rich repeat protein 3a , protein after-hours , protein overtime , F-box and leucine-rich repeat protein 3 , F-box/LRR-repeat protein 3-like , f-box/LRR-repeat protein 3-like

GENE ID	SPEZIES
26224	Homo sapiens
50789	Mus musculus
306129	Rattus norvegicus
428048	Gallus gallus
446817	Xenopus laevis
485499	Canis lupus familiaris
540712	Bos taurus
548882	Xenopus (Silurana) tropicalis
699028	Macaca mulatta
100010986	Monodelphis domestica
100052811	Equus caballus
100169937	Ovis aries
100413726	Callithrix jacchus
100450887	Pongo abelii
100556180	Anolis carolinensis
831688	Arabidopsis thaliana
100081796	Ornithorhynchus anatinus
100469040	Ailuropoda melanoleuca
100580993	Nomascus leucogenys
100152980	Sus scrofa
100730124	Cavia porcellus
100350003	Oryctolagus cuniculus
378451	Danio rerio

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Show all anti-F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) Antikörper with Pubmed References

Human F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) Interaktionspartner

Mouse (Murine) F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with F-Box and Leucine-Rich Repeat Protein 3 (FBXL3)

Bezeichner auf Proteinebene für FBXL3