PGC Produkte
(Pepsinogen C (PGC))
Kategorien
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009].
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Ausgewählte PGC Kategorien
PGC Antikörper
High quality antibodies with extensive validation data.
PGC ELISA Kits
Reliable ELISA kits for a wide range of species.
PGC Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PGC Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7431245
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, ICC, IF
Validierungen
- (3)
Kat. Nr.
ABIN6266376
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (2)
Kat. Nr.
ABIN518828
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PGC ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (5)
Kat. Nr.
ABIN6730888
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (5)
Kat. Nr.
ABIN6574145
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958438
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PGC Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314794
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN6387837
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7389107
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PGC Produkten
: "Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity." in: Nature communications, Vol. 9, Issue 1, pp. 2419, (2019) (PubMed).: "Troy is expressed in human stomach mucosa and a novel putative prognostic marker of intestinal type gastric cancer." in: Oncotarget, Vol. 8, Issue 31, pp. 50557-50569, (2017) (PubMed).
: "Introduction of Sd(a) carbohydrate antigen in gastrointestinal cancer cells eliminates selectin ligands and inhibits metastasis." in: Cancer research, Vol. 65, Issue 14, pp. 6220-7, (2005) (PubMed).
Synonyme und alternative Namen zu PGC
progastricsin (pepsinogen C) (PGC), progastricsin (PGC), progastricsin (pepsinogen C) (Pgc), progastricsin (Pgc), 2210410L06Rik, CPGC, gastricsin, Gastricsin, PEPC, Pg-1, PG1, PGC, PGII, PGNC, Upg-1, Upg1Bezeichner auf Proteinebene für PGC
- gastricsin
- pepsinogen C
- pepsin C
- pepsinogen group II
- preprogastricsin
- urinary pepsinogen 1
- Urinary pepsinogen 1
- gastricsin-like
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