This is a synthetic peptide designed for use in combination with anti-VEGFA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
VEGFA
Reaktivität: Human, Maus, Ratte
Wirt: Synthetic
BP
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
VEGFA
(Vascular Endothelial Growth Factor A (VEGFA))
Hintergrund
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome.
Alias Symbols: MGC70609, MVCD1, VEGF, VPF
Protein Interaction Partner: HIF1A,RB1,ADAMTS1,FLT1,FLT1,KDR,KDR,KDR,NRP1,NRP1,NRP2,NRP2,ADAMTS1,AKT1,CSDA,CTGF,EPHB2,FLT1,GPC1,IGFBP7,KDR,NRP1,NRP2,PGF,SEMA3F,SPARC,TNXB,VEGFA,VEGFB,VTN,YBX1,ADAMTS1,CTGF,GPC1,HSP90AA1,HSPA4,IGFBP7,KDR,NRP1,PGF,SPARC,VEGFA,VTN