Thioredoxin Interacting Protein (TXNIP) Peptid
TXNIP
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN985779
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Thioredoxin Interacting Protein (TXNIP) Peptid (ABIN985779)
Target
TXNIP
(Thioredoxin Interacting Protein (TXNIP))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TXNIP antibody (Catalog #: ARP52193_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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Hintergrund
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TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
Alias Symbols: EST01027, HHCPA78, THIF, VDUP1
Protein Interaction Partner: KPNA2,TXN,HDAC1,KPNA2,SCEL,SMURF2,TXN,TXNRD1,ZBTB16,ZBTB32,HDAC1,SCEL,TXN,ZBTB16,ZBTB32
Protein Size: 391 -
Molekulargewicht
- 44 kDa
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Gen-ID
- 10628
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NCBI Accession
- NM_006472, NP_006463
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UniProt
- Q9H3M7
Target
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