Thioredoxin Interacting Protein (TXNIP) Peptid
Kurzübersicht für Thioredoxin Interacting Protein (TXNIP) Peptid (ABIN937587)
Target
Spezies
Quelle
Applikation
-
-
Protein-Typ
- Synthetic
-
Sequenz
- DTPEAPPCYM DVIPEDHRLE SPTTPLLDDM DGSQDSPIFM YAPEFKFMPP
-
Produktmerkmale
-
A synthetic peptide for use as a blocking control in assays to test for specificity of TXNIP antibody,
Alternative Names: TXNIP control peptide, TXNIP antibody Blocking Peptide, Anti-TXNIP Blocking Peptide, Thioredoxin Interacting Protein Blocking Peptide, EST01027 Blocking Peptide, HHCPA78 Blocking Peptide, THIF Blocking Peptide, VDUP1 Blocking Peptide
-
-
-
-
Applikationshinweise
- Optimal conditions should be determined by the investigator
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handhabung
- Avoid repeated freeze/thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C long term.
-
-
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
-
Hintergrund
- TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
-
Molekulargewicht
- 44 kDa
Target
-