Protein Tob1 (TOB1) (Middle Region) Peptid
TOB1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN985359
Kurzübersicht für Protein Tob1 (TOB1) (Middle Region) Peptid (ABIN985359)
Target
Protein Tob1 (TOB1)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- DLLKQKAISS SMHSLYGLGL GSQQQPQQQQ QPAQPPPPPP PPQQQQQQKT
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TOB1 Antibody(ARP52105_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Protein Tob1 (TOB1)
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Hintergrund
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This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
Alias Symbols: APRO6, MGC104792, MGC34446, PIG49, TOB, TROB, TROB1
Protein Interaction Partner: CNOT7,ERBB2,MAPK1,MARCKS,SCMH1,SETDB1,SMAD1,SMAD2,SMAD3,SMAD4,SMAD5,SMAD6,SMAD9,CNOT7,MAPK1,MAPK9,MARCKS,PABPC1,RPS6KA1,SCMH1,SETDB1,SKP2,SMAD1,SMAD4,SMAD5,SMAD9,UBC
Protein Size: 345 -
Molekulargewicht
- 38 kDa
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Gen-ID
- 10140
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NCBI Accession
- NM_005749, NP_005740
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UniProt
- P50616
Target
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