A synthetic peptide for use as a blocking control in assays to test for specificity of TOB1 antibody, Alternative Names: TOB1 control peptide, TOB1 antibody Blocking Peptide, Anti-TOB1 Blocking Peptide, transducer of ERBB2, 1 Blocking Peptide, APRO6 Blocking Peptide, MGC104792 Blocking Peptide, MGC34446 Blocking Peptide, PIG49 Blocking Peptide, TOB Blocking Peptide, TROB Blocking Peptide, TROB1 Blocking Peptide, TOB1, TOB-1, TOB 1, TOB-1 Blocking Peptide, TOB 1 Blocking Peptide
This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins.