Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1) (Middle Region) Peptid
TNKS1BP1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN985332
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1) (Middle Region) Peptid (ABIN985332)
Target
TNKS1BP1
(Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TNKS1BP1 antibody (Catalog #: ARP58347_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
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Hintergrund
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TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
Alias Symbols: FLJ45975, KIAA1741, TAB182
Protein Interaction Partner: TNKS,TNKS2,TNKS,TNKS2
Protein Size: 1729 -
Molekulargewicht
- 190 kDa
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Gen-ID
- 85456
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NCBI Accession
- NM_033396, NP_203754
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UniProt
- Q9C0C2
Target
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