A synthetic peptide for use as a blocking control in assays to test for specificity of TNKS1 BP1 antibody, Alternative Names: TNKS1BP1 control peptide, TNKS1BP1 antibody Blocking Peptide, Anti-TNKS1BP1 Blocking Peptide, Tankyrase 1 Binding Protein 1 182Kda Blocking Peptide, FLJ45975 Blocking Peptide, KIAA1741 Blocking Peptide, TAB182 Blocking Peptide
TNKS1BP1
Reaktivität: Human
Wirt: Synthetic
BP, BI
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
TNKS1BP1
(Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
Hintergrund
TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.