Transcription Factor A, Mitochondrial (TFAM) Peptid
Kurzübersicht für Transcription Factor A, Mitochondrial (TFAM) Peptid (ABIN984970)
Target
Spezies
Quelle
Applikation
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TFAM antibody (Catalog #: ARP36992_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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Hintergrund
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TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: Hmgts, mtTFA, tsHMG, AI661103
Protein Size: 243 -
Molekulargewicht
- 27 kDa
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Gen-ID
- 21780
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NCBI Accession
- NM_009360, NP_033386
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UniProt
- P40630
Target
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