Transcription Factor A, Mitochondrial (TFAM) Peptid
Kurzübersicht für Transcription Factor A, Mitochondrial (TFAM) Peptid (ABIN984969)
Target
Spezies
Quelle
Applikation
-
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Transcription Factor AntibodiesAM antibody (Catalog #: ARP31400_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
-
Hintergrund
-
The function remains unknown.This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: TCF6, MtTF1, mtTFA, TCF6L1, TCF6L2, TCF6L3
Protein Interaction Partner: NRF1,PNP,TFB1M,TFB2M,TFB1M,TFB2M
Protein Size: 246 -
Molekulargewicht
- 29 kDa
-
Gen-ID
- 7019
-
NCBI Accession
- NM_003201, NP_003192
-
UniProt
- Q00059
Target
-