Transcription Factor A, Mitochondrial (TFAM) Peptid
TFAM
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN984969
Kurzübersicht für Transcription Factor A, Mitochondrial (TFAM) Peptid (ABIN984969)
Target
TFAM
(Transcription Factor A, Mitochondrial (TFAM))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Transcription Factor AntibodiesAM antibody (Catalog #: ARP31400_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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Hintergrund
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The function remains unknown.This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: TCF6, MtTF1, mtTFA, TCF6L1, TCF6L2, TCF6L3
Protein Interaction Partner: NRF1,PNP,TFB1M,TFB2M,TFB1M,TFB2M
Protein Size: 246 -
Molekulargewicht
- 29 kDa
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Gen-ID
- 7019
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NCBI Accession
- NM_003201, NP_003192
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UniProt
- Q00059
Target
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