Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (Middle Region) Peptid
SPG20
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN984337
Kurzübersicht für Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (Middle Region) Peptid (ABIN984337)
Target
SPG20
(Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- ASWVSWGLVK GAEITGKAIQ KGASKLRERI QPEEKPVEVS PAVTKGLYIA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SPG20 Antibody(ARP55162_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
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Hintergrund
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This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
Alias Symbols: KIAA0610, SPARTIN, TAHCCP1
Protein Interaction Partner: EPS15,SMURF2,TUBA1A,ZFYVE9,ITCH,TUBA1A
Protein Size: 666 -
Molekulargewicht
- 73 kDa
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Gen-ID
- 23111
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NCBI Accession
- NM_015087, NP_055902
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UniProt
- Q8N0X7
Target
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