Suppressor of Cytokine Signaling 1 (SOCS1) (Middle Region) Peptid
SOCS1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für Suppressor of Cytokine Signaling 1 (SOCS1) (Middle Region) Peptid (ABIN984227)
Target
SOCS1
(Suppressor of Cytokine Signaling 1 (SOCS1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- RQRNCFFALS VKMASGPTSI RVHFQAGRFH LDGSRESFDC LFELLEHYVA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SOCS1 Antibody(ARP42148_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Suppressor of Cytokine Signaling 1 (SOCS1) peptide
SOCS1 Reaktivität: Human, Rind (Kuh), Maus, Ratte, Hund Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
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Hintergrund
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SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. SOCS1 functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of its gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Alias Symbols: CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
Protein Interaction Partner: AXL,CSF1R,FLT3,FYN,GRB2,IGF1R,INSR,ITK,KIT,NCK1,PDGFRB,PIK3R2,TEK,VAV1,VAV2,AXL,COMMD1,CSF1,CSF1R,CXCR4,EGFR,FLT3,FYN,GHR,GRB2,IFNGR1,IGF1R,IL2RB,INSR,IRS1,IRS2,ITK,JAK1,JAK2,JAK3,KIT,MPL,NCK1,PDGFRB,PIK3R1,PIK3R2,PIM2,RELA,TCEB1,TCEB2,TEC,TEK,TIRAP,TRIM8
Protein Size: 211 -
Molekulargewicht
- 23 kDa
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Gen-ID
- 8651
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NCBI Accession
- NM_003745, NP_003736
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UniProt
- O15524
Target
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