Stratifin (SFN) (Middle Region) Peptid
SFN
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN983633
Kurzübersicht für Stratifin (SFN) (Middle Region) Peptid (ABIN983633)
Target
14-3-3 sigma/SFN (SFN)
(Stratifin (SFN))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SFN antibody (Catalog #: ARP54792_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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Hintergrund
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SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
Alias Symbols: YWHAS
Protein Interaction Partner: TP53,TP53,ABL1,BAD,BAX,BCR,CCAR1,CDC25B,CDK1,CHST1,EEF1A1,EGFR,EIF2S1,EIF4B,FAM189A2,GPRIN2,HDAC5,HNRNPD,ING1,KCNK15,KCNK3,KCNK9,KIAA0408,MAP3K5,MARK3,MDM4,MST1R,NR3C1,PLEKHF2,PLK4,TBL3,TRIM25,TSC2,WDYHV1,YWHAG,ZFP36,ABLIM1,ANKS1A,APC,APLP2,ARAF,ARHGAP11A,ARHGAP21,ARHGAP32,ARHGEF16,ARHGEF17,ARHGEF5,BAD,BCAR1,BRAF,CDK1,CGN,CHEK1,CHST1,CSNK2A1,CYTH2,DCAF7,DTX2,DYRK1A,ERRFI1,FAM189A2,GAN,GPRIN2,GRB7,HDAC4,HDAC7,HNRNPU,IRS1,IRS2,ISCU,ITCH,JUB,KIAA0408,KIF23,KIF5B,KLC1,KLC2,KLHDC2,LAD1,LMO7,LSR,MAGI1,MAP3K2,MAPKAP1,MARK1,MARK2,MARK3,MDM2,MPRIP,MYCBP2,NEDD4L,NR3C1,OSBPL3,PAK4,PARD3,PARD3B,PI4KB,PIK3C2B,PKP2,PKP3,PLEKHF2,PLK4,PPFIBP1,PPFIBP2,PPP1R3D,PTOV1,PTPN2,PTPN3,RACGAP1,RAE1,RAF1,RALGPS2,RHPN2,RND3,SASH1,SAV1,SH2D3A,SH3BP4,SHCBP1,SHROOM3,SIPA1L1,SIPA1L3,SORBS2,SPIRE1,SRRM2,SRSF10,ST5,SYNJ2,TBL3,TJP2,TNK1,TNS4,TP53,TRIM25,TRIM32,UBC,USP8,WDYHV1,WEE1,YWHAG,ZAK,ZNF638
Protein Size: 248 -
Molekulargewicht
- 28 kDa
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Gen-ID
- 2810
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NCBI Accession
- NM_006142, NP_006133
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UniProt
- P31947
Target
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