Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Peptid
SF3B1
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle SF3B1 Produkte
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SF3B1 antibody (Catalog #: ARP40248_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
- Hintergrund
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SF3B1 is the subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome.
Alias Symbols: MDS, PRP10, Hsh155, PRPF10, SAP155, SF3b155
Protein Interaction Partner: SF3B14,U2AF1,U2AF2,DYRK1A,MELK,PPP1R8,SF3B14,SF3B3,SMAD1,SMAD5,SMAD9,SNIP1,TCERG1,ATG12,BRF2,CCNE1,CDC5L,DDX42,GSK3B,HDAC3,PHF5A,PPP1R8,PUF60,RNPS1,RNU11,RNU12-2P,SAP130,SF3A2,SF3B14,SF3B2,SF3B3,SF3B4,SF3B5,SMNDC1,SNRNP40,TCERG1,YWHAZ
Protein Size: 789 - Molekulargewicht
- 87 kDa
- Gen-ID
- 23451
- NCBI Accession
- NM_001005526
- UniProt
- O75533
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