Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Peptid
SF3B1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN983622
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Peptid (ABIN983622)
Target
SF3B1
(Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SF3B1 antibody (Catalog #: ARP40733_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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Hintergrund
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SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.
Alias Symbols: MDS, PRP10, Hsh155, PRPF10, SAP155, SF3b155
Protein Interaction Partner: SF3B14,U2AF1,U2AF2,DYRK1A,MELK,PPP1R8,SF3B14,SF3B3,SMAD1,SMAD5,SMAD9,SNIP1,TCERG1,ATG12,BRF2,CCNE1,CDC5L,DDX42,GSK3B,HDAC3,PHF5A,PPP1R8,PUF60,RNPS1,RNU11,RNU12-2P,SAP130,SF3A2,SF3B14,SF3B2,SF3B3,SF3B4,SF3B5,SMNDC1,SNRNP40,TCERG1,YWHAZ
Protein Size: 789 -
Molekulargewicht
- 87 kDa
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Gen-ID
- 23451
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NCBI Accession
- NM_001005526
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UniProt
- Q7Z497
Target
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