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Regulator of G-Protein Signaling 4 (RGS4) Peptid

RGS4 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN982937
  • Target Alle RGS4 Produkte
    RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-RGS4 antibody (Catalog #: ARP30213_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
    Hintergrund
    Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.

    Alias Symbols: MGC2124, MGC60244, RGP4, SCZD9

    Protein Interaction Partner: CALM1,COPB1,COPB2,ERBB3,GNAI1,GNAI2,GNAO1,GNAQ,PLCB1,PTAFR,COPB2,ERBB3,GNAI1,GNAI1,GNAI2,GNAI2,GNAI3,GNAO1,GNAQ,GNAQ,GNAT1

    Protein Size: 205
    Molekulargewicht
    23 kDa
    Gen-ID
    5999
    NCBI Accession
    NM_005613, NP_005604
    UniProt
    P49798
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