Regulator of G-Protein Signaling 4 (RGS4) (C-Term) Peptid
Kurzübersicht für Regulator of G-Protein Signaling 4 (RGS4) (C-Term) Peptid (ABIN982938)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Sequenz
- IFNLMEKDSY RRFLKSRFYL DLVNPSSCGA EKQKGAKSSA DCASLVPQCA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RGS4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
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Hintergrund
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Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
Alias Symbols: DKFZp761F1924, MGC2124, MGC60244, RGP4, SCZD9
Protein Interaction Partner: CALM1,COPB1,COPB2,ERBB3,GNAI1,GNAI2,GNAO1,GNAQ,PLCB1,PTAFR,COPB2,ERBB3,GNAI1,GNAI1,GNAI2,GNAI2,GNAI3,GNAO1,GNAQ,GNAQ,GNAT1
Protein Size: 302 -
Molekulargewicht
- 34 kDa
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Gen-ID
- 5999
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NCBI Accession
- NM_001102445, NP_001095915
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UniProt
- A7XA59
Target
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