RNA Binding Motif Protein 5 (RBM5) (N-Term) Peptid
RBM5
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle RBM5 Produkte
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RBM5 antibody (Catalog #: ARP38684_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
- Synonyme
- wu:fc25a08 Peptide, wu:fe06f12 Peptide, g15 Peptide, h37 Peptide, luca15 Peptide, rbm5 Peptide, rmb5 Peptide, RBM5 Peptide, G15 Peptide, LUCA15 Peptide, RMB5 Peptide, D030069N10Rik Peptide, RNA binding motif protein 5 Peptide, RNA binding motif protein 5 S homeolog Peptide, RNA binding motif protein 5 L homeolog Peptide, rbm5 Peptide, rbm5.S Peptide, RBM5 Peptide, rbm5.L Peptide, Rbm5 Peptide
- Hintergrund
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RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Alias Symbols: FLJ39876, G15, H37, LUCA15, RMB5
Protein Interaction Partner: C1orf103,C1orf103
Protein Size: 815 - Molekulargewicht
- 92 kDa
- Gen-ID
- 10181
- NCBI Accession
- NM_005778, NP_005769
- UniProt
- P52756
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