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RNA Binding Motif Protein 5 (RBM5) Peptid

RBM5 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938939
382,12 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 20 bis 27 Werktagen

Kurzübersicht für RNA Binding Motif Protein 5 (RBM5) Peptid (ABIN938939)

Target

RBM5 (RNA Binding Motif Protein 5 (RBM5))

Spezies

Säugetier

Quelle

  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    GSDKRVSRTE RSGRYGSIID RDDRDERESR SRRRDSDYKR SSDDRRGDRY

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of RBM5 antibody,
    Alternative Names: RBM5 control peptide, RBM5 antibody Blocking Peptide, Anti-RBM5 Blocking Peptide, RNA binding motif protein 5 Blocking Peptide, FLJ39876 Blocking Peptide, G15 Blocking Peptide, H37 Blocking Peptide, LUCA15 Blocking Peptide, RMB5 Blocking Peptide, RBM5, RBM-5, RBM 5, RBM-5 Blocking Peptide, RBM 5 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    RBM5 (RNA Binding Motif Protein 5 (RBM5))

    Hintergrund

    RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.

    Molekulargewicht

    92 kDa
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