This is a synthetic peptide designed for use in combination with anti-RANBP1 antibody (Catalog #: ARP46083_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
RANBP1
(RAN Binding Protein 1 (RANBP1))
Synonyme
MGC64314 Peptide, zeh1094 Peptide, zgc:85649 Peptide, hm:zeh1094 Peptide, wu:fa96a09 Peptide, wu:fj39g07 Peptide, HTF9A Peptide, Htf9a Peptide, RAN binding protein 1 S homeolog Peptide, RAN binding protein 1 L homeolog Peptide, ran binding protein 1 Peptide, RAN binding protein 1 Peptide, ran-specific GTPase-activating protein pseudogene Peptide, ranbp1.S Peptide, ranbp1.L Peptide, PVX_090070 Peptide, GL50803_16969 Peptide, LOC100343953 Peptide, ranbp1 Peptide, RANBP1 Peptide, Ranbp1 Peptide
Hintergrund
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC88701, HTF9A
Protein Interaction Partner: CD93,CD93,RAN,RANGRF,RCC1,KPNB1,MPG,RAN,XPO1