A synthetic peptide for use as a blocking control in assays to test for specificity of RANBP1 antibody, Alternative Names: RanBP1 control peptide, RanBP1 antibody Blocking Peptide, Anti-RanBP1 Blocking Peptide, Ran Binding Protein 1 Blocking Peptide, MGC88701 Blocking Peptide, RanBP1, RanBP-1, RanBP 1, RanBP-1 Blocking Peptide, RanBP 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
RANBP1
(RAN Binding Protein 1 (RANBP1))
Synonyme
MGC64314 Peptide, zeh1094 Peptide, zgc:85649 Peptide, hm:zeh1094 Peptide, wu:fa96a09 Peptide, wu:fj39g07 Peptide, HTF9A Peptide, Htf9a Peptide, RAN binding protein 1 S homeolog Peptide, RAN binding protein 1 L homeolog Peptide, ran binding protein 1 Peptide, RAN binding protein 1 Peptide, ran-specific GTPase-activating protein pseudogene Peptide, ranbp1.S Peptide, ranbp1.L Peptide, PVX_090070 Peptide, GL50803_16969 Peptide, LOC100343953 Peptide, ranbp1 Peptide, RANBP1 Peptide, Ranbp1 Peptide
Hintergrund
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23 kDa protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.