RAN Binding Protein 1 (RANBP1) Peptid
Kurzübersicht für RAN Binding Protein 1 (RANBP1) Peptid (ABIN939753)
Target
Spezies
Quelle
Applikation
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Protein-Typ
- Synthetic
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Sequenz
- KFEECRKEIE EREKKAGSGK NDHAEKVAEK LEALSVKEET KEDAEEKQ
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of RANBP1 antibody,
Alternative Names: RanBP1 control peptide, RanBP1 antibody Blocking Peptide, Anti-RanBP1 Blocking Peptide, Ran Binding Protein 1 Blocking Peptide, MGC88701 Blocking Peptide, RanBP1, RanBP-1, RanBP 1, RanBP-1 Blocking Peptide, RanBP 1 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- RANBP1 (RAN Binding Protein 1 (RANBP1))
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Hintergrund
- Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23 kDa protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
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Molekulargewicht
- 23 kDa
Target
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