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Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) (Middle Region) Peptid

PPP1R8 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN982113
  • Target Alle PPP1R8 Produkte
    PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 10
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PPP1R8 antibody (Catalog #: ARP40411_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
    Synonyme
    ARD-1 Peptide, ARD1 Peptide, NIPP-1 Peptide, NIPP1 Peptide, PRO2047 Peptide, 6330548N22Rik Peptide, AU044684 Peptide, PPP1R8 Peptide, ard-1 Peptide, ard1 Peptide, nipp-1 Peptide, nipp1 Peptide, ppp1r8 Peptide, si:ch211-206a7.1 Peptide, protein phosphatase 1 regulatory subunit 8 Peptide, protein phosphatase 1, regulatory subunit 8 Peptide, protein phosphatase 1, regulatory (inhibitor) subunit 8 Peptide, protein phosphatase 1, regulatory subunit 8b Peptide, protein phosphatase 1 regulatory subunit 8 L homeolog Peptide, protein phosphatase 1, regulatory subunit 8a Peptide, protein phosphatase 1 regulatory subunit 8 S homeolog Peptide, PPP1R8 Peptide, Ppp1r8 Peptide, ppp1r8b Peptide, ppp1r8.L Peptide, ppp1r8a Peptide, ppp1r8.S Peptide
    Hintergrund
    This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

    Alias Symbols: ARD-1, ARD1, NIPP-1, NIPP1, PRO2047

    Protein Interaction Partner: C14orf1,C7orf64,CDC5L,CRMP1,CSNK2A1,CSNK2A2,EED,GBP2,HDAC2,LYN,MELK,PPP1CA,PPP1CC,PRKACA,SETDB1,SF3B1,STC2,C14orf1,C7orf64,CRMP1,EED,GBP2,HDAC2,LYN,NME2,PPP1CA,PPP1CB,PPP1CC,PRKACA,SETDB1,SF3B1,STC2

    Protein Size: 351
    Molekulargewicht
    38 kDa
    Gen-ID
    5511
    NCBI Accession
    NM_014110, NP_054829
    UniProt
    Q12972
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