A synthetic peptide for use as a blocking control in assays to test for specificity of PPP1 R8 antibody, Alternative Names: PPP1R8 control peptide, PPP1R8 antibody Blocking Peptide, Anti-PPP1R8 Blocking Peptide, Protein Phosphatase 1 Regulatory Inhibitor Subunit 8 Blocking Peptide, ARD-1 Blocking Peptide, ARD1 Blocking Peptide, NIPP-1 Blocking Peptide, NIPP1 Blocking Peptide, PRO2047 Blocking Peptide, PPP1R8, PPPR8-1, PPPR8 1, PPPR8-1 Blocking Peptide, PPPR8 1 Blocking Peptide
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.