Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) (Middle Region) Peptid
PARP11
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981359
Kurzübersicht für Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) (Middle Region) Peptid (ABIN981359)
Target
PARP11
(Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PARP11 antibody (Catalog #: ARP33767_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
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Hintergrund
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PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
Alias Symbols: C12orf6, DKFZp779H0122
Protein Interaction Partner: GTPBP3,DCAF11,GTPBP3,LYZ,NUP98,OTUD4,RNF114
Protein Size: 331 -
Molekulargewicht
- 39 kDa
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Gen-ID
- 57097
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NCBI Accession
- NM_020367, NP_065100
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UniProt
- Q9NR21
Target
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