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Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) Peptid

PARP11 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939406
  • Target Alle PARP11 Produkte
    PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    IKHGNTFQIH GVSLQQRHLF RTYKSMFLAR VLIGDYINGD SKYMRPPSKD
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of PARP11 antibody,
    Alternative Names: PARP11 control peptide, PARP11 antibody Blocking Peptide, Anti-PARP11 Blocking Peptide, Adp-Ribose Polymerase 11 Blocking Peptide, C12orf6 Blocking Peptide, DKFZp779H0122 Blocking Peptide, Poly (ADP-ribose) polymerase 11 Blocking Peptide, PARP11, PARP-11, PARP 11, PARP-11 Blocking Peptide, PARP 11 Blocking Peptide
    Aufreinigung
    Serum
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
    Synonyme
    5330431N24Rik Peptide, AI851877 Peptide, ARTD11 Peptide, HIN1L Peptide, C12orf6 Peptide, parp11 Peptide, MGC82612 Peptide, PARP11 Peptide, RGD1561791 Peptide, poly (ADP-ribose) polymerase family, member 11 Peptide, poly(ADP-ribose) polymerase family member 11 Peptide, poly(ADP-ribose) polymerase family member 11 S homeolog Peptide, poly(ADP-ribose) polymerase family member 11 L homeolog Peptide, Parp11 Peptide, PARP11 Peptide, parp11.S Peptide, parp11.L Peptide, parp11 Peptide
    Hintergrund
    PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
    Molekulargewicht
    39 kDa
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