Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) (Middle Region) Peptid
Kurzübersicht für Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) (Middle Region) Peptid (ABIN8108434)
Target
Quelle
Applikation
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Protein Region
- Middle Region
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Verwendungszweck
- PARP11 Peptide - middle region
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-PARP11 antibody ( ARP33767_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
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Hintergrund
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Background Information: PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
Alternative Symbols: C12orf6, DKFZp779H0122
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Molekulargewicht
- 39kDa
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Gen-ID
- 57097
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NCBI Accession
- NP_065100
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UniProt
- Q9NR21
Target
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