N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (Middle Region) Peptid
NECAB3
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle NECAB3 Produkte
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
- Protein Region
- Middle Region
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- ESVEAQSRLC GSRRAGRRAL RSVSRSSTWS PGSSDTGRSS EAEMQWRLQV
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NECAB3 Antibody(ARP57670_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
- Hintergrund
-
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: APBA2BP, EFCBP3, NIP1, STIP3, SYTIP2, XB51, dJ63M2.4, dJ63M2.5
Protein Interaction Partner: APBA2,APP,APBA2,IKBKG
Protein Size: 396 - Molekulargewicht
- 44 kDa
- Gen-ID
- 63941
- NCBI Accession
- NM_031232, NP_112509
- UniProt
- Q96P71
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