N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) Peptid
Kurzübersicht für N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) Peptid (ABIN938135)
Target
Spezies
Quelle
Applikation
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Protein-Typ
- Synthetic
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Sequenz
- ESVEAQSRLC GSRRAGRRAL RSVSRSSTWS PGSSDTGRSS EAEMQWRLQV
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of NECAB3 antibody,
Alternative Names: NECAB3 control peptide, NECAB3 antibody Blocking Peptide, Anti-NECAB3 Blocking Peptide, N-Terminal Ef-Hand Calcium Binding Protein 3 Blocking Peptide, APBA2BP Blocking Peptide, EFCBP3 Blocking Peptide, NIP1 Blocking Peptide, STIP3 Blocking Peptide, SYTIP2 Blocking Peptide, XB51 Blocking Peptide, dJ63M2.4 Blocking Peptide, dJ63M2.5 Blocking Peptide, NECAB3, NECAB-3, NECAB 3, NECAB-3 Blocking Peptide, NECAB 3 Blocking Peptide -
Aufreinigung
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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Hintergrund
- The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
- 44 kDa
Target
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