O6-Methylguanine-DNA-Methyltransferase (MGMT) (Middle Region) Peptid
MGMT
Reaktivität: Human
Wirt: Synthetic
BP, WB
-
- Target Alle MGMT Produkte
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Protein Region
- Middle Region
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- ISYQQLAALA GNPKAARAVG GAMRGNPVPI LIPCHRVVCS SGAVGNYSGG
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MGMT Antibody(ARP42038_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Hintergrund
-
MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Alias Symbols: -
Protein Interaction Partner: CREBBP,CSNK2A1,EP300,PRKACA,PRKCA,UBA1,HIST4H4,ACTB,ANP32E,ANXA1,ANXA2,CCNB1,CDK1,CDK10,CDK12,CDK2,CDKL5,CDKN1A,CREBBP,CSNK2A1,CSNK2A2,DDX24,DDX5,EEF1A1,EEF1A2,EEF1B2,EIF3H,EP300,ESR1,FBL,FBXO2,FBXO27,H2BFM,HIST1H2AM,HIST1H4A,HIST3H3,HNRNPA2B1,HNRNPC,HSP9
Protein Size: 207 - Molekulargewicht
- 22 kDa
- Gen-ID
- 4255
- NCBI Accession
- NM_002412, NP_002403
- UniProt
- P16455
-
Sie sind hier:
